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PITH OF CURRENT LITERATURE. 91 jould be given the very best possible chance at the Compare Generic Viagra Prices (rliest possible opportunity; and the mere fact that tatment has a very dubious effect on the chara- j;er of the Wassermann reaction, instead of sug- j sting to us the impossibility of curing congenital iphilis. should stimulate us, on the contrary, to mtinue treatment, possibly for years, Compare Generic Viagra Prices instead of, i is so frequently the case, stopping treatment as Compare Generic Viagra Prices Rabbits, By Marks. Experimental Studies Concerning the Lethal Dose of the Acid Solution of Ehrlich-Hata's "606," By Hering. . Treatment of Syphilis with Arsenobenzol, By Weiler. ; Possibility of Thrombosis after Intravenous Infusions of Arsenbenzol, By Hausmann. ( The Nature and Importance of Anaphylaxia, By Friedberger. ; The Clinical Significance of the So Called Pagets Cancer of the Breast, Compare Generic Viagra Prices By Hirschel. 1 Practical Experiences with Mandelbaum's Serodiag- nostic Typhoid Reaction, By AsT. Compare Generic Viagra Prices I Treatment of Chronic Obstipation with Compare Generic Viagra Prices Paraffin Sup- positories. By LiPOWSKi. .\ New Method of Irradiation with the X Rays, By SCHWENTER. Inhalation Treatment, By Christen. Rare Stenoses of the Larynx. By Gr.^ff. Zykloform, a New Wound Ansesthetic, By Str.'VUSS. Facial Paralysis in Food Poisoning, By Erben. -■Mbrecht Kossel, By Cohxheim. J. Effect of "606" upon Experimental Vac- ( ation of Rabbits. — Marks found that if the I .ximuin du.'-e, o.i per kilogramme, was injected i ^ the veins immediately after the vaccination the 1 ction of the latter was wholly prevented ; 0.08 c ild prevent the reaction if introduced at the same 1 le as the lymph, while 0.05 was too small a dose t produce any effect. Intravenous injection of the I ximum Compare Generic Viagra Prices dose twenty-four hours after the vaccina- \ n was inefficient and did not prevent the reaction. 5. Lethal Dose of "606." — Herinsr found the I lal doses of a one half per cent, solution of "606'' i rabbits and in dogs per kilogramine. From these I tries to calculate the possible lethal dose for man, I : this is uncertain because we do not know ' ether man is more or less resistant to the remedy 1 n rabbits or than dogs, which differ markedly in 1 5 respect. \. "606." — Weiler gives an analysis of his « es with full clinical histories of a large number. ( Compare Generic Viagra Prices the whole his results correspond with the many \ t have already been published, but he contributes ! ew aflditional symptoms produced by the injec- i n. Thus he says that several patients complained I irtly after the injection of difficulty in urination, i 1 that this condition persisted in one patient for E eral days. Obstipation was also noticed a num- 1 ■ of times. Many complained of a great feeling t thirst, and the appetite was often poor for a few Tie did not notice Compare Generic Viagra Prices any notable effect on psori- craris. lichen planus, warts, or pointed con- I it.i. Of the 206 patients treated only forty *, lid be kept under observation, and among these were fourteen recurrences. These cases are de- scribed in full. Compare Generic Viagra Prices Two patients with tabes were im- proved in their general condition. 5. Thrombosis after Intravenous Infusion. — Hausmann reports a case of thrombosis following intravenous infusion of "606." One month after the infusion a thrombosed piece of vein, 3.5 cm. long, was resected and found to contain Streptococcus alb us. 6. Anaphylaxia. — Friedberger defines ana- phylaxia as the excessive sensitiveness of the animal organism to the addition of foreign albumin not through the intestinal tract. This addition of for- eign albumin forms antibodies in the organism which with the aid of the complement, on a second injection of the saine albumin, form from it intense and rapidly acting poisons. The serum of an animal previously treated in this manner may carry this con- dition of oversensitiveness passively to a normal ani- mal, or it may act poisoningly. The product formed in all forms of anaphylaxia may be obtained in the test tube and is known as anaphylatoxine. 7. Paget's Cancer of the Breast. — Hirschel is of the opinion that every chronic eczema of the nip- ple should be treated and observed with the greatest possible care and that when the diagnosis is uncer- tain a portion should be excised for examination, be- cause there riiay exist in the mamma a small carcino- ma which has secondarily produced the eczema, a permanent cure of which may be expected from earlv extirpation. He prefers the term cancerous eczema of the breast as better than that of Paget's breast cancer, and calls attention to the fact that Paget's idea that carcinoma originated from the eczema is tlie exact opposite of the truth, that the carcinoma is pri- mary in these cases. WIENER KLINISCHE WOCHENSCHRIFT December S, 1910.